Staphylococcus aureus , Panton-Valentine leukocidin, and necrotising pneumonia

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Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia.

The Staphylococcus aureus Panton-Valentine leukocidin (PVL) is a pore-forming toxin secreted by strains epidemiologically associated with the current outbreak of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and with the often-lethal necrotizing pneumonia. To investigate the role of PVL in pulmonary disease, we tested the pathogenicity of clinical isolates, isogenic...

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Panton-Valentine leukocidin-positive staphylococcus aureus necrotising pneumonia complicating pandemic A(H1N1) influenza infection.

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Panton-Valentine Leukocidin Genes in Staphylococcus aureus

To the Editor: The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue infections, particularly furuncu...

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Panton-Valentine Leukocidin–producing Staphylococcus aureus

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ژورنال

عنوان ژورنال: BMJ

سال: 2005

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.331.7520.793